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KMID : 0358819830100030285
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Journal of Korean Society of Plastic and Reconstructive Surgeons
1983 Volume.10 No. 3 p.285 ~ p.294
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EXPERIMENTAL STUDY FOR THE DERMAL MICROCIRCULATION AFTER BURING IN THE RATS; THE EFFECTS OF COLD WATER THERAPY AND 10% ACETYL SALICYLIC OINTMENT TREATMENT
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Ahn Hee-Chang
Lew Jai-Mann
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Abstract
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In all skin burns, there exists a zone of stasis which is not immediately coagulated but which shows a progressive compromise in microvascular circulation with a complete cessation of dermal perfusion by 24 hours. The cold-water therapy and 10% acetyl salicylic acid ointment treatment were evaluated for their ability to prevent dermal ischemia in standardized partial-thickness burns in the rats.
The results of our experiments as follows;
1) In untreated group, the perfusion only up to the level of the dermal plexus was shown at 12 hours and there was no dermal perfusion of the india ink at 24 hours.
2) In cold-water therapy group, although some diminution of microcirculation in superficial vessels was noted, the section of skin showed a persistence ofindia-ink filling up to the level of dermal plexus and higher by 24 hours and a near normal perfusion by 72 hours.
3) 10% acetyl salicylic acid ointment treatment group maintained perfusion up to subpapillary plexus by 24 hours.
It appears from these studies that the cold water therapy and 10% acetyl salicylic acid ointment treatment after burning may be effective in preventing the progressive changes and in improving dermal perfusion. So these treatments may lead to lessening the depth and amount of skin necrosis after a burn.
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